Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane.

Jie Yin, Kuang-Yui M Chen, Mary J Clark, Mahdi Hijazi, Punita Kumari, Xiao-chen Bai, Roger K Sunahara, Patrick Barth, Daniel M Rosenbaum. Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane. Nature. 2020. Aug;584(7819):125-129.

Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter.

Yan Wang, Yan Han, Ji She, Nam X Nguyen, Vamsi K Mootha, Xiao-chen Bai, Youxing Jiang. Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter. eLife. 2020. Aug 7;9.

Structural and mechanistic regulation of the Pro-degenerative NAD hydrolase SARM1.

Matthew Bratkowski, Tian Xie, Desiree A Thayer, Shradha Lad, Prakhyat Mathur, Yu-San Yang, Gregory Danko, Thomas C Burdett, Jean Danao, Aaron Cantor, Jennifer A Kozak, Sean P Brown, Xiaochen Bai, Shilpa Sambashivan. Structural and mechanistic regulation of the Pro-degenerative NAD hydrolase SARM1. Cell Reports. 2020. Aug 4;32(5):107999.

Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations.

Jing Xue, Tian Xie, Weizhong Zeng, Youxing Jiang, Xiao-chen Bai†. Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations. eLife. 2020. Jul 29;9.

Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway

Xuewu Zhang, Xiao-chen Bai†, Zhijian J Chen†. Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway. Immunity. 2020. Jul 14;53(1):43-53.

Cryo-EM structure of the human cohesin-NIPBL-DNA complex.

Zhubing Shi, Haishan Gao, Xiao-chen Bai†, Hongtao Yu†. Cryo-EM structure of the human cohesin-NIPBL-DNA complex. Science. 2020. Jun 26;368(6498):1454-1459.

Cryo-EM structures of the human cation-chloride cotransporter KCC1.

Si Liu, Shenghai Chang, Binming Han, Lingyi Xu, Mingfeng Zhang, Cheng Zhao, Wei Yang, Feng Wang, Jingyuan Li†, Eric Delpire†, Sheng Ye†, Xiao-chen Bai†, Jiangtao Guo†. Cryo-EM structures of the human cation-chloride cotransporter KCC1. Science. 2019. Oct 25;366(6464):505-508.

Structural basis of the activation of type 1 insulin-like growth factor receptor

Jie Li*, Eunhee Choi*†, Hongtao Yu†, Xiao-chen Bai†. Structural basis of the activation of type 1 insulin-like growth factor receptor. Nature Communications 2019;10 (1), 1-11

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands

Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
Jie Li*, Guijun Shang*, Yu-Ju Chen, Chad A Brautigam, Jen Liou, Xuewu Zhang†, Xiao-chen Bai†, eLife 2019;8: e47650.

Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex

Emiko Uchikawa*, Eunhee Choi†*, Guijun Shang , Hongtao Yu†, Xiao-chen Bai†. Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. eLife 2019;8:e48630.