Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex

Emiko Uchikawa*, Eunhee Choi†*, Guijun Shang , Hongtao Yu†, Xiao-chen Bai†. Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. eLife 2019;8:e48630.