The rabbit RyR1 in open conformation

The endolysosomal TRPML1 channel in nanodiscs

The first structure determined using the UTSW’s new $17 million Cryo-Electron Microscopy Facility

Structural studies of ion channels and transporters

The calcium-activated, non-selective cation channel TRPM4

The mammalian TPC1 channel in both closed and open states

These structures reveal how phosphoinositide activate the ion channel.

The fungal mitochondrial calcium uniporter

The cryo-EM structure was determined by using the Volta phase plate

The full-length STING in both apo and CGAMP bound states

A 80 kDa membrane protein was determined by cryo-EM

STING bound with TBK1

The structure reveals that the C-terminal tail of STING is bound to TBK1

The human TPC2 channel in both closed and open states

The proton channel OTOP3

The cryo-EM structure of OTOP3 from Xenopus tropicalis (XtOTOP3)