3D DNA-origami object

3D DNA-origami object

Movie Processing

Movie processing

Approach to compensate for beam-induced particles movement

The yeast eIF5B initiationDetermining a relatively high-resolution structure of the eIF5B-ribosome complex from a very small fraction of particles complex

The yeast eIF5B initiation complex

Determining a relatively high-resolution structure of the eIF5B-ribosome complex from a very small fraction of particles

The yeast mitochondrial large ribosomal subunitThe first high resolution cryo-EM structure of mitochondrial ribosome

The yeast mitochondrial large ribosomal subunit

The first high resolution cryo-EM structure of mitochondrial ribosome

The Dark apoptosome

The apoptosome from Drosophila

The human γ-secretase

The first high resolution cryo-EM structure of γ-secretase

The γ-secretase in complex with DAPT

Masked classification with residual signal subtraction

A method of dealing with local structural heterogeneity