3D DNA-origami object

3D DNA-origami object

Movie Processing

Movie processing

Approach to compensate for beam-induced particles movement

The yeast eIF5B initiationDetermining a relatively high-resolution structure of the eIF5B-ribosome complex from a very small fraction of particles complex

The yeast eIF5B initiation complex

Determining a relatively high-resolution structure of the eIF5B-ribosome complex from a very small fraction of particles

The yeast mitochondrial large ribosomal subunitThe first high resolution cryo-EM structure of mitochondrial ribosome

The yeast mitochondrial large ribosomal subunit

The first high resolution cryo-EM structure of mitochondrial ribosome

The Plasmodium falciparum 80S ribosome bound to the drug emetine

The rabbit ryanodine receptor RyR1 in closed state

The Dark apoptosome

The apoptosome from Drosophila

The human γ-secretase

The first high resolution cryo-EM structure of γ-secretase

The γ-secretase in complex with DAPT

Masked classification with residual signal subtraction

A method of dealing with local structural heterogeneity