PlexinC1/A39R 2:2 dimeric complex

Human ZnT8, a Zn2+/H+ antiporter in the insulin secretory granules, determined in the inward-facing conformation. This study provides the structural insights into the Zn2+/H+ exchange mechanism of ZnT8

SARM1 in the auto-inhibited state

Scap alone or with Insig bound. This study reveals a large rotation of the luminal L1-L7 domain upon the binding of Scap to Insig.

C-MET/HGF 2:2 asymmetric complexes in the active state. This study reveals that one HGF molecule is sufficient to induce a specific dimerization mode of c-MET by utilizing two distinct interfaces